What is Nexium?
Esomeprazole is a proton pump inhibitor (PPI), a drug that is used to reduce acid secretion in the stomach.
Some of the conditions, esomeprazole may be prescribed for include: Dyspepsia, Peptic ulcer, Gastroesophageal reflux disorder, Zollinger‑Ellison syndrome.
Mechanism and Pharmacokinetics
Esomeprazole reduces acid secretion by inhibiting an enzyme called H+/K+ ATPase, which is present in gastric parietal cells.
Esomeprazole is acid labile and is administered orally as enteric‑coated granules.
Absorption of esomeprazole is rapid, with peak plasma levels occurring approximately 1–2 hours after dose.
The absolute bioavailability is 64% after a single dose of 40 mg and increases to 89% after repeated once daily administration.
Uses and Dosage
Esomeprazole is used to treat heartburn and certain other conditions caused by too much acid in the stomach.
Gastroesophageal reflux disease (GERD), where stomach acid backs up into your esophagus.
To treat or help prevent ulcers.
Usually, a single oral dose of 20 to 40 mg per day is recommended and can lead to a peak plasma or blood concentration of 0.5 to 1.0 mg/L within 1 to 4 hours of intake.
Side Effects & Safety
The most common side effects of esomeprazole are headache, diarrhea, nausea, gas, stomach pain, constipation, dry mouth, dizziness (esomeprazole IV).
Common side effects include headache, nausea, abdominal pain, and dry mouth.
Treatment with proton pump inhibitors may lead to slightly increased risk of gastrointestinal infections such as Salmonella and Campylobacter and, in hospitalised patients, possibly also Clostridium difficile.
Recent studies suggest that there may be a slight increase in the risk of bone fractures when proton pump inhibitors like esomeprazole are taken for longer than a year.
Long‑Term Use Concerns
While less common, Nexium can also lead to potentially serious side effects that require immediate medical attention.
Studies have linked prolonged PPI therapy to an increased risk of certain conditions, such as: 1. Increased risk of bone fractures 2. Chronic kidney disease 3. Community‑acquired pneumonia.
Brand vs Generic
Esomeprazole, sold under the brand name Nexium ... is used to treat gastroesophageal reflux disease, peptic ulcer disease, and Zollinger‑Ellison syndrome.
Esomeprazole is the (S)-(−)-enantiomer (or less specifically the S‑isomer) of omeprazole. It works by blocking H^+/K^+-ATPase in the parietal cells of the stomach.
Generic versions of esomeprazole magnesium are available worldwide.
Online Purchase & Prescription
It is available over‑the‑counter under the brand name Nexium in the United States and the UK.
Esomeprazole is used to treat a range of digestive problems caused by excess stomach acid...
Esomeprazole is not an emergency solution for dealing with heartburn. It’s a longer‑term treatment option to prevent chronic problems and help already‑damaged areas of the digestive tract to heal.
Experience Reports from Forums
I took Nexium off and on for about 7 years. It helped me a lot, and I never got any side effects or long term damage after taking it for that long.
Nexium was a life saver for me when my gastritis was at its worst and nothing else helped.
I have been on nexium for 2 months now ... Lightheadedness, dizziness, and for me the worst was the muscle and joint pain.
Buying Nexium Online
Buy Nexium and start using a reliable treatment for that frequent heartburn bothering you.
Nexium is a popular and effective medication for treating the symptoms of gastroesophageal reflux disease (GERD) and other problems in which the stomach produces too much acid.
You’ve come to the right place! Nexium is a prescription medication, it can not be obtained over the counter.
Order and buy now to get rid of frequent heartburn, and start living your life to the fullest.
Availability in Hong Kong Districts
Fanda in Central and TST will likely sell it or its generic without a prescription. Fanda definitely have it for sale over the counter.
| 20 mg 360 pills | HK$ 2.34 |
| 20 mg 270 pills | HK$ 2.57 |
| 20 mg 180 pills | HK$ 2.88 |
| 20 mg 120 pills | HK$ 3.19 |
| 20 mg 90 pills | HK$ 3.58 |
| 20 mg 60 pills | HK$ 3.97 |
| 20 mg 30 pills | HK$ 4.98 |
| 40 mg 180 pills | HK$ 4.13 |
| 40 mg 120 pills | HK$ 4.59 |
| 40 mg 90 pills | HK$ 5.14 |
| 40 mg 60 pills | HK$ 5.68 |
| 40 mg 30 pills | HK$ 7.08 |